I would not use cologuard again. Twice their test was positive. My Dr said first the positive might have been wrong. So I took the test again. Second was also positive. Now the problem came down to being able to schedule a colonoscopy. I was very concerned and getting an apt was difficult. The colonoscopy was negative. The Dr actually did 2 colonoscopies on me because of 2 positive tests. Both negative. Cologuard cost me a lot of unneeded anxiety, and expense.